Cigarette smoking substantially alters plasma microRNA profiles in healthy subjects.

  title={Cigarette smoking substantially alters plasma microRNA profiles in healthy subjects.},
  author={Kei S Takahashi and Shin-Ichi Yokota and Naoyuki Tatsumi and Tatsuki Fukami and Tsuyoshi Yokoi and Miki Nakajima},
  journal={Toxicology and applied pharmacology},
  volume={272 1},
Circulating microRNAs (miRNAs) are receiving attention as potential biomarkers of various diseases, including cancers, chronic obstructive pulmonary disease, and cardiovascular disease. However, it is unknown whether the levels of circulating miRNAs in a healthy subject might vary with external factors in daily life. In this study, we investigated whether cigarette smoking, a habit that has spread throughout the world and is a risk factor for various diseases, affects plasma miRNA profiles. We… CONTINUE READING


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