Cigarette smoking and aneuploidy in human sperm
@article{Shi2001CigaretteSA, title={Cigarette smoking and aneuploidy in human sperm}, author={Q. Shi and E. Ko and L. Barclay and T. Hoang and A. Rademaker and R. Martin}, journal={Molecular Reproduction and Development}, year={2001}, volume={59} }
Cigarette smoke contains chemicals which are capable of inducing aneuploidy in experimental systems. These chemicals have been shown to reach the male reproductive system, increasing oxidative DNA damage in human sperm and lowering semen quality. We have examined the association between smoking and aneuploid sperm by studying 31 Chinese men with similar demographic characteristics and lifestyle factors except for cigarette smoking. None of the men drank alcohol. These men were divided into… CONTINUE READING
Topics from this paper
128 Citations
Effect of lifestyle exposures on sperm aneuploidy
- Biology, Medicine
- Cytogenetic and Genome Research
- 2005
- 84
- Highly Influenced
Differential sensitivity of male germ cells to mainstream and sidestream tobacco smoke in the mouse.
- Biology, Medicine
- Toxicology and applied pharmacology
- 2009
- 33
- PDF
Smoking-induced chromosomal segregation anomalies identified by FISH analysis of sperm
- Biology, Medicine
- Molecular Cytogenetics
- 2014
- 11
The effects of male age on sperm DNA damage in healthy non-smokers.
- Biology, Medicine
- Human reproduction
- 2007
- 191
- PDF
Cigarette smoking affects specific sperm oxidative defenses but does not cause oxidative DNA damage in infertile men.
- Biology, Medicine
- Fertility and sterility
- 2010
- 30
The relationship between exposure to air pollution and sperm disomy
- Biology, Medicine
- Environmental and molecular mutagenesis
- 2015
- 37
Smoking‐induced genetic and epigenetic alterations in infertile men
- Biology, Medicine
- Andrologia
- 2018
- 14
- PDF
References
SHOWING 1-10 OF 15 REFERENCES
Smoking cigarettes is associated with increased sperm disomy in teenage men.
- Biology, Medicine
- Fertility and sterility
- 1998
- 235
Aneuploidy in sperm and exposure to fungicides and lifestyle factors
- Biology, Medicine
- Environmental and molecular mutagenesis
- 1999
- 89
Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men
- Biology, Medicine
- Environmental and molecular mutagenesis
- 1997
- 156
Spontaneous frequencies of aneuploid and diploid sperm in 10 normal Chinese men: assessed by multicolor fluorescence in situ hybridization
- Biology, Medicine
- Cytogenetic and Genome Research
- 2000
- 38
Smoking and reproduction: gene damage to human gametes and embryos.
- Medicine, Biology
- Human reproduction update
- 2000
- 376
- PDF
Abnormalities for chromosomes 13 and 21 detected in spermatozoa from infertile men.
- Biology, Medicine
- Human reproduction
- 1998
- 79
- PDF
Aneuploidy in human sperm: the use of multicolor FISH to test various theories of nondisjunction.
- Biology, Medicine
- American journal of human genetics
- 1996
- 139
Donor age and the frequency of disomy for chromosomes 1, 13, 21 and structural abnormalities in human spermatozoa using multicolour fluorescence in-situ hybridization.
- Biology, Medicine
- Human reproduction
- 1998
- 64
- PDF