Cigarette smokers self-administer intravenous nicotine.

  title={Cigarette smokers self-administer intravenous nicotine.},
  author={Jack E. Henningfield and Katsumasa Miyasato and Donald R. Jasinski},
  journal={Pharmacology, biochemistry, and behavior},
  volume={19 5},
Human volunteers who smoked cigarettes were given the opportunity to press a lever that resulted in intravenous injections of saline or nicotine. Nicotine injections were taken in orderly patterns that were related to unit dose, whereas patterns of saline injections varied widely. Furthermore, the volunteers reported that nicotine produced subjective effects similar to those produced by administration of abuse drugs such as morphine or cocaine. 

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 56 extracted citations

Do smokers self-administer pure nicotine? A review of the evidence

Psychopharmacology • 2004
View 9 Excerpts
Highly Influenced

Skin contamination as pathway for nicotine intoxication in vapers.

Toxicology in vitro : an international journal published in association with BIBRA • 2017
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…