Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor.

@article{Kirkham2003CigaretteST,
  title={Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor.},
  author={Paul A. Kirkham and Gillian Spooner and Claire Ffoulkes-Jones and Ronan Calvez},
  journal={Free radical biology & medicine},
  year={2003},
  volume={35 7},
  pages={697-710}
}
Pulmonary emphysema in chronic obstructive pulmonary disease (COPD) is characterized by the destruction of the alveolar walls leading to permanent enlargement of distal respiratory air spaces. A major causal factor is cigarette smoking, which produces conditions of chronic oxidative stress within the lungs. At a cellular level, increased macrophage… CONTINUE READING