Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells

@inproceedings{Cello2013CigaretteSI,
  title={Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells},
  author={Francescopaolo di Cello and Vera Lynn Flowers and Huili Li and Briana Vecchio-Pag{\'a}n and Brent Gordon and Kirsten M Harbom and James Shin and R. Matthew Beaty and Wei Wang and Cory Brayton and Stephen B. Baylin and Cynthia A. Zahnow},
  booktitle={Molecular Cancer},
  year={2013}
}
Recent epidemiological studies demonstrate that both active and involuntary exposure to tobacco smoke increase the risk of breast cancer. Little is known, however, about the molecular mechanisms by which continuous, long term exposure to tobacco smoke contributes to breast carcinogenesis because most previous studies have focused on short term treatment models. In this work we have set out to investigate the progressive transforming effects of tobacco smoke on non-tumorigenic mammary epithelial… CONTINUE READING
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Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer

  • F Di Cello, L Cope, +4 authors CA Zahnow
  • PLoS One 2013,
  • 2013
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