Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

Abstract

Wingless/integrase-1 (WNT) signalling is associated with lung inflammation and repair, but its role in chronic obstructive pulmonary disease (COPD) pathogenesis is unclear. We investigated whether cigarette smoke-induced dysregulation of WNT-5B contributes to airway remodelling in COPD.We analysed WNT-5B protein expression in the lung tissue of COPD… (More)
DOI: 10.1183/13993003.01541-2015

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Cite this paper

@article{Heijink2016CigaretteSE, title={Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.}, author={Irene H. Heijink and Harold G. de Bruin and Robin Dennebos and Marnix R. Jonker and Jacobien A. Noordhoek and Corry-Anke Brandsma and Maarten van den Berge and Dirkje S Postma}, journal={The European respiratory journal}, year={2016}, volume={48 2}, pages={504-15} }