Cigarette smoke increases Staphylococcus aureus biofilm formation via oxidative stress.

@article{Kulkarni2012CigaretteSI,
  title={Cigarette smoke increases Staphylococcus aureus biofilm formation via oxidative stress.},
  author={Ritwij Kulkarni and Swati Antala and Alice Wang and F{\'a}bio E. Amaral and Ryan Rampersaud and Samuel J Larussa and Paul J. Planet and Adam J Ratner},
  journal={Infection and immunity},
  year={2012},
  volume={80 11},
  pages={3804-11}
}
The strong epidemiological association between cigarette smoke (CS) exposure and respiratory tract infections is conventionally attributed to immunosuppressive and irritant effects of CS on human cells. Since pathogenic bacteria such as Staphylococcus aureus are members of the normal microbiota and reside in close proximity to human nasopharyngeal cells, we hypothesized that bioactive components of CS might affect these organisms and potentiate their virulence. Using Staphylococcus aureus as a… CONTINUE READING
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