Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection.

@article{Eddleston2011CigaretteSD,
  title={Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection.},
  author={Jane M Eddleston and Rachel U Lee and Astrid M Doerner and Jack H. Herschbach and Bruce L Zuraw},
  journal={American journal of respiratory cell and molecular biology},
  year={2011},
  volume={44 1},
  pages={118-26}
}
Exposure to cigarette smoke is associated with a significant increase in the risk for respiratory viral infections. The airway epithelium is the primary target for both cigarette smoke and respiratory viral infection. We investigated the effects of cigarette smoke on the response of airway epithelial cells to rhinovirus infection. We found that pre-exposure of BEAS-2B cells or primary normal human bronchial epithelial cells (NHBEs) to cigarette smoke extract (CSE) reduced the induction of mRNA… CONTINUE READING
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