Cigarette smoke and muscle catabolism in C2 myotubes

  title={Cigarette smoke and muscle catabolism in C2 myotubes},
  author={O. Rom and S. Kaisari and D. Aizenbud and A. Reznick},
  journal={Mechanisms of Ageing and Development},
  • O. Rom, S. Kaisari, +1 author A. Reznick
  • Published 2013
  • Chemistry, Medicine
  • Mechanisms of Ageing and Development
  • Previous studies have revealed evidence of muscular damage and up-regulation of genes associated with impaired muscle maintenance in smokers. Cigarette smoking has also been associated with sarcopenia, the age-related loss of muscle mass and strength. In order to investigate the cellular mechanisms by which cigarette smoke (CS) promotes muscle catabolism, C2 myotubes from an in vitro skeletal muscle cell line, were exposed to different levels of whole vapor phase CS using a controlled CS… CONTINUE READING
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