Cigarette and Nicotine Chewing Gum Toxicity in Children

@article{Smolinske1988CigaretteAN,
  title={Cigarette and Nicotine Chewing Gum Toxicity in Children},
  author={Susan C. Smolinske and David G. Spoerke and S.K. Spiller and Kathleen M. Wruk and Kenneth W. Kulig and B.H. Rumackt},
  journal={Human \& Experimental Toxicology},
  year={1988},
  volume={7},
  pages={27 - 31}
}
A prospective review of 51 cases of tobacco ingestion and 5 cases of nicotine resin chewing gum exposure was conducted to evaluate the incidence and degree of toxicity caused by these products in children. A dose-response relationship was observed for cigarette exposures. Nine of 10 children ingesting more than one cigarette or three cigarette butts developed signs or symptoms, while 12 of 24 ingesting lesser amounts became symptomatic (P < 0.01). Severe symptoms (e.g. limb jerking and… 
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References

SHOWING 1-10 OF 14 REFERENCES
Acute Intoxication with Nicotine Alkaloids and Cannabinoids in Children from Ingestion of Cigarettes
The risks to children from tobacco and tobacco with cannabinoids have been described following ingestion of cigarettes, cigarette butts, reefers and joints (Arena, 1974; Schvartsman, 1971; Dreisbach,…
Plasma nicotine levels produced by chewing nicotine gum.
TLDR
In a short-term study, nicotine gum proved an acceptable source of nicotine for aiding smoking cessation and few side effects were seen with the use of either the 2- or 4-mg gum.
Atrial fibrillation while chewing nicotine gum.
TLDR
A man with known cardiovascular disease who developed atrial fibrillation while chewing nicotine gum is reported here in a case of a 52-year-old male smoker with known coronary artery disease who sought help in order to stop smoking.
Absorption and metabolism of nicotine from cigarettes.
TLDR
Eight men volunteers each smoked a single cirgarette containing 14C-nicotine and gave arterial blood samples during and for 50 minutes after smoking, finding the peak arterial nicotine concentrations bore a similar relationship to the intravenous dose, as did the peak nicotine concentrations to the retained doses during smoking.
Nicotine Overdose after a Single Piece of Nicotine Gum
TLDR
1 Qureshi 5, Wagner HN Jr., Alderson P0, et al. improved left ventricular diastolic filling in patients with coronary artery disease after percutaneous transluminal coronary angioplasty.
Chronic nicotine ingestion and atrial fibrillation.
Paroxysmal atrial fibrillation occurred in a fit 35 year old man who consumed large doses of nicotine chewing gum (Nicorette Leo) over a prolonged period.
Tobacco Poisoning with Sino‐Auricular Block
TLDR
A case of sino‐auricular block due to nicotine poisoning is described, and a short review of the literature on the subject is given.
1985 Annual Report of the American Association of Poison Control Centers National Data Collection System.
A computerized case file for acute poisoning in man-the first year's experience
Tobaksforgiftning hos born
  • Ugeskrift For Laeger
  • 1984
...
1
2
...