Cigarette Smoking and Colorectal Cancer Risk by KRAS Mutation Status Among Older Women

@article{Samadder2012CigaretteSA,
  title={Cigarette Smoking and Colorectal Cancer Risk by KRAS Mutation Status Among Older Women},
  author={Niloy Jewel Samadder and Robert A Vierkant and Lori S. Tillmans and Alice H. Wang and Charles F. Lynch and Kristin E. Anderson and Amy J. French and Robert W Haile and Lisa J. Harnack and John D. Potter and Susan L. Slager and Thomas C. Smyrk and Stephen N. Thibodeau and James R. Cerhan and Paul J. Limburg},
  journal={The American Journal of Gastroenterology},
  year={2012},
  volume={107},
  pages={782-789}
}
OBJECTIVES:Existing data support a modest association between cigarette smoking and incident colorectal cancer (CRC) overall. In this study, we evaluated associations between cigarette smoking and CRC risk stratified by KRAS mutation status, using data and tissue resources from the Iowa Women's Health Study (IWHS).METHODS:The IWHS is a population-based cohort study of cancer incidence among 41,836 randomly selected Iowa women, ages 55–69 years of age at enrollment (1986). Exposure data… CONTINUE READING