Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine-Induced HepG2 Cells.

@article{Zhu2015CichoricAR,
  title={Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine-Induced HepG2 Cells.},
  author={Di Zhu and Yutang Wang and Qingwei Du and Zhigang Liu and Xuebo Liu},
  journal={Journal of agricultural and food chemistry},
  year={2015},
  volume={63 51},
  pages={
          10903-13
        }
}
Cichoric acid, a caffeic acid derivative found in Echinacea purpurea, basil, and chicory, has been reported to have bioactive effects, such as anti-inflammatory, antioxidant, and preventing insulin resistance. In this study, to explore the effects of CA on regulating insulin resistance and chronic inflammatory responses, the insulin resistance model was constructed by glucosamine in HepG2 cells. CA stimulated glucosamine-mediated glucose uptake by stimulating translocation of the glucose… 

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