Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death.

@article{Harris1993ChylomicronsAT,
  title={Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death.},
  author={Hobart W. Harris and Carl Grunfeld and Kenneth R. Feingold and T E Read and John P. Kane and A. L. Jones and E B Eichbaum and G F Bland and Joseph H. Rapp},
  journal={The Journal of clinical investigation},
  year={1993},
  volume={91 3},
  pages={1028-34}
}
The hypertriglyceridemia of infection was traditionally thought to represent the mobilization of substrate to fuel the body's response to the infectious challenge. However, we have previously shown that triglyceride-rich lipoproteins can protect against endotoxin-induced lethality. The current studies examine the mechanism by which this protection occurs. Rats infused with a lethal dose of endotoxin preincubated with chylomicrons had a reduced mortality compared with rats infused with endotoxin… CONTINUE READING
53 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Similar Papers

Loading similar papers…