Churg-Strauss syndrome in two patients receiving montelukast.

@article{Guilpain2002ChurgStraussSI,
  title={Churg-Strauss syndrome in two patients receiving montelukast.},
  author={Philippe Guilpain and J. F. Viallard and Philippe Lagarde and Pascal Cohen and Marianne Kambouchner and J L Pellegrin and Lo{\"i}c Guillevin},
  journal={Rheumatology},
  year={2002},
  volume={41 5},
  pages={535-9}
}
OBJECTIVE Churg-Strauss syndrome (CSS) has been described in association with the treatment of asthmatic patients with leukotriene receptor antagonist. The main mechanism proposed to explain this condition is the unmasking of CSS after the leukotriene receptor antagonist has allowed corticosteroid tapering. Other hypotheses might be proposed. METHODS We describe two patients who developed CSS after starting treatment with montelukast, a new antileukotriene drug. RESULTS Both patients… CONTINUE READING

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