Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node.

@article{Yasuda1982ChronotropicEO,
  title={Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node.},
  author={I. Yasuda and Tadashi Hirano and Keisuke Amaha and Hiroto Fudeta and Shigeru Obara},
  journal={Anesthesiology},
  year={1982},
  volume={57 4},
  pages={
          289-92
        }
}
The mechanism of bradycardia caused by the administration of succinylcholine has not been fully elucidated. Accordingly, the effects of succinylcholine and succinylmonocholine on the sinoatrial node were studied in 35 mongrel dogs. The sinus node artery was selectively perfused with autologous blood from a femoral artery at a constant pressure of 100 mmHg, and 30 to 1,000 micrograms of succinylcholine or succinylmonocholine was administered directly into the artery. Succinylcholine caused a… CONTINUE READING