Chronotherapy of Trichlormethiazide in Hypertensive Patients

@article{Fujimura1991ChronotherapyOT,
  title={Chronotherapy of Trichlormethiazide in Hypertensive Patients},
  author={A. Fujimura and K. Ohashi and A. Ebihara},
  journal={The Journal of Clinical Pharmacology},
  year={1991},
  volume={31}
}
  • A. Fujimura, K. Ohashi, A. Ebihara
  • Published 1991
  • Medicine
  • The Journal of Clinical Pharmacology
  • Circadian influence of trichlormethiazide on serum electrolyte levels, lipid levels, and glucose levels were evaluated in 12 hypertensive patients. One tablet of trichlormethiazide (2 mg) was given once a day at 7:00 am or 7:00 pm for 8 weeks. The study was done by a crossover design. Twenty—four‐hour urine was collected, and fasting blood samples were obtained during the control period and at the end of each treatment period. The 24‐hour urine level increased slightly after treatment with… CONTINUE READING
    2 Citations

    References

    SHOWING 1-10 OF 20 REFERENCES
    Circadian influence on effect of propranolol on exercise-induced tachycardia in healthy subjects
    • 14
    Chronopharmacological Study of Nitrendipine in Healthy Subjects
    • 19
    Timing optimizes sustained‐release indomethacin treatment of osteoarthritis
    • 82
    Chronopharmacological study of furosemide in rats.
    • 27
    Circadian time dependence of cisplatin urinary kinetics
    • 62
    Hypertension, the potassium ion and impaired carbohydrate tolerance.
    • J. W. Conn
    • Medicine
    • The New England journal of medicine
    • 1965
    • 329