Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders.


Sleep, a mysterious behavior, has recently been recognized as a crucial factor for health and longevity. The daily sleep/wake cycle provides the basis of biorhythms controlling whole-body homeostasis and homeodynamics; therefore, disruption of sleep causes several physical and psychological disorders, including cardiovascular disease, obesity, diabetes… (More)
DOI: 10.1016/j.pharmthera.2017.12.010