Chronically HIV-1-infected monocytic cells induce apoptosis in cocultured T cells.

@article{Chen1998ChronicallyHM,
  title={Chronically HIV-1-infected monocytic cells induce apoptosis in cocultured T cells.},
  author={Huaibin Chen and Y. K. Yip and Ines George and Max Tyorkin and Erez Salik and K. Sperber},
  journal={Journal of immunology},
  year={1998},
  volume={161 8},
  pages={4257-67}
}
We have previously developed a human macrophage hybridoma model system to study the effect of HIV-1 infection on monocytic function. Upon coculture of one chronically (35 days postinfection) HIV-1-infected human macrophage hybridoma cell line, 43HIV, there was a dose-dependent decrease in the viability of cocultured Ag-stimulated T cells associated with an… CONTINUE READING