Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases

@article{Portenoy1986ChronicUO,
  title={Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases},
  author={Russell K. Portenoy and Kathleen M. Foley},
  journal={Pain},
  year={1986},
  volume={25},
  pages={171-186}
}
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837 Citations
Highly Influential Citations
17
Background Citations
170
Methods Citations
9
Results Citations
7

837 Citations

[Oral opioids in patients with non-malignant pain.].

The results show that patients with musculo-skeletal and deafferentation pain respond better to opioids than patients with headache, and opioids are justifiable for the treatment of non-malignant pain and can be given without danger over a long period of time.

Effectiveness of opioids in the treatment of chronic non-cancer pain.

There is weak evidence that long-term opioid therapy with morphine and transdermal fentanyl not only decreases pain but also improves functioning, and there is limited or lack of evidence for all other controlled substances, including the most commonly used drugs.

[Opioids for treating non malignant chronic pain: the role of methadone.].

Oral methadone is cost-effective and an effective alternative for a better pain control in certain patients, and may be an important alternative for treating non-malignant chronic pain, especially neuropathic pain.

The use of nonopioid drugs in management of chronic orofacial pain.

  • J. Zuniga
  • Medicine, Psychology
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • 1998

Role of Opioid Analgesics in the Treatment of Chronic Non-Cancer Pain

The role of opioids in non-cancer pain will therefore remain controversial while there is a lack of controlled studies investigating their use in the long term treatment of this condition.

Long-term oral opioid therapy in patients with chronic nonmalignant pain.

Orale Opiattherapie bei Patienten mit “nicht-malignen” Schmerzen

The results show that patients with musculo-skeletal and deafferentation pain respond better to opioids than patients with headache and that opioids are justifiable for the treatment of non-malignant pain and can be given without danger over a long period of time.

Randomised trial of oral morphine for chronic non-cancer pain

Chronic noncancer pain and the long term utility of opioids.

CNCP can be treated by opioids safely and with a modest effect, with improvement in functioning in some patients who are refractory to other measures, and opioids may even be used effectively for patients with a history of chemical dependency.

Opioid Substitution to Improve the Effectiveness of Chronic Noncancer Pain Control: A Chart Review

It was showed that if a patient receiving chronic opioid therapy experiences an intolerable side effect or if the drug is ineffective, changing to a different opioid may result in a lessening or elimination of the side effect and/or improved analgesia.
...

References

SHOWING 1-10 OF 82 REFERENCES

Management of cancer pain with parenteral medication.

Oral analgesic administration offers simplicity and economy, avoids the discomforts and potential complications of repeated injections, makes the patient less dependent on others for his care, and may even obviate the need for hospitalization in some cases.

Outpatient treatment of prescription opioid dependence: comparison of two methods.

Pain which was masked by opioid dependency and which emerged during detoxification proved to be an insurmountable barrier to total withdrawal in the majority of patients.

PATTERNS OF NARCOTIC DRUG USE IN A CANCER PAIN CLINIC *

This article reviews the limited available data on the use of narcotics in patients with chronic medical illness and the own experience in treating patients with pain due to cancer, to determine the patterns of narcotic drug usage.

Management of pain during debridement: a survey of U.S. burn units

Drug utilization patterns in chronic pain patients

Long-term use of narcotic analgesics in chronic pain.

Prescribing practices for pain in drug dependence: a lesson in ignorance.

A literature review shows an amazing paucity of rigorous research in Chronic pain patients which supports the widely held belief that medications contribute to dysfunction in chronic pain thus patients require detoxification.

Problems with the use of oxycodone compound in patients with chronic pain

Drug abuse and dependency in patients with chronic pain.

Early detection and treatment of drug abuse should minimize some of the difficulties involved in management of treatment-resistive patients with chronic pain.

CHANGES IN PERSONALITY AND SUBJECTIVE EXPERIENCE ASSOCIATED WITH THE CHRONIC ADMINSTRATION AND WITHDRAWAL OF OPIATES

The immediate subjective feeling of usefulness of morphine or heroin for settling symptoms was more highly correlated with the intensity of opiate withdrawal symptoms than with psychopathic traits, and neurotic traits, including hypochondriasis, increased during the chronic phase but was not evident after a single dose of morphine.
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