Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases

@article{Portenoy1986ChronicUO,
  title={Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases},
  author={Russell K. Portenoy and Kathleen M. Foley},
  journal={Pain},
  year={1986},
  volume={25},
  pages={171-186}
}
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836 Citations
Highly Influential Citations
17
Background Citations
170
Methods Citations
9
Results Citations
7

836 Citations

[Oral opioids in patients with non-malignant pain.].

The results show that patients with musculo-skeletal and deafferentation pain respond better to opioids than patients with headache, and opioids are justifiable for the treatment of non-malignant pain and can be given without danger over a long period of time.

Effectiveness of opioids in the treatment of chronic non-cancer pain.

There is weak evidence that long-term opioid therapy with morphine and transdermal fentanyl not only decreases pain but also improves functioning, and there is limited or lack of evidence for all other controlled substances, including the most commonly used drugs.

[Opioids for treating non malignant chronic pain: the role of methadone.].

Oral methadone is cost-effective and an effective alternative for a better pain control in certain patients, and may be an important alternative for treating non-malignant chronic pain, especially neuropathic pain.

The use of nonopioid drugs in management of chronic orofacial pain.

  • J. Zuniga
  • Medicine, Psychology
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • 1998

Role of Opioid Analgesics in the Treatment of Chronic Non-Cancer Pain

The role of opioids in non-cancer pain will therefore remain controversial while there is a lack of controlled studies investigating their use in the long term treatment of this condition.

Long-term oral opioid therapy in patients with chronic nonmalignant pain.

Orale Opiattherapie bei Patienten mit “nicht-malignen” Schmerzen

The results show that patients with musculo-skeletal and deafferentation pain respond better to opioids than patients with headache and that opioids are justifiable for the treatment of non-malignant pain and can be given without danger over a long period of time.

Randomised trial of oral morphine for chronic non-cancer pain

Chronic noncancer pain and the long term utility of opioids.

CNCP can be treated by opioids safely and with a modest effect, with improvement in functioning in some patients who are refractory to other measures, and opioids may even be used effectively for patients with a history of chemical dependency.

Opioid Substitution to Improve the Effectiveness of Chronic Noncancer Pain Control: A Chart Review

It was showed that if a patient receiving chronic opioid therapy experiences an intolerable side effect or if the drug is ineffective, changing to a different opioid may result in a lessening or elimination of the side effect and/or improved analgesia.
...

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Pain which was masked by opioid dependency and which emerged during detoxification proved to be an insurmountable barrier to total withdrawal in the majority of patients.

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