Chronic treatment with selective I2-imidazoline receptor ligands decreases the content of pro-apoptotic markers in rat brain

@article{Garau2013ChronicTW,
  title={Chronic treatment with selective I2-imidazoline receptor ligands decreases the content of pro-apoptotic markers in rat brain},
  author={C. Garau and A. Miralles and J. Garc{\'i}a-Sevilla},
  journal={Journal of Psychopharmacology},
  year={2013},
  volume={27},
  pages={123 - 134}
}
Selective I2-imidazoline receptor ligands induce neuroprotection through various molecular mechanisms including blockade of N-methyl-D-aspartate (NMDA) receptors. To investigate new neuroprotective mechanisms associated with I2-imidazoline receptors, the effects of selective (2-styryl-2-imidazoline (LSL 61122), 2-(2-benzofuranyl)-2-imidazoline (2-BFI), 2-(4,5-dihydroimidazol-2-yl) quinoline hydrochloride (BU-224)) and non-selective (idazoxan) I2-drugs on canonical apoptotic pathways were… Expand
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