Chronic treatment with aripiprazole induces differential gene expression in the rat frontal cortex.

@article{Cheng2008ChronicTW,
  title={Chronic treatment with aripiprazole induces differential gene expression in the rat frontal cortex.},
  author={Min-Chih Cheng and Ding-Lieh Liao and Chao A. Hsiung and Chih-yu Chen and Yu-Chieh Liao and Chia-Hsiang Chen},
  journal={The international journal of neuropsychopharmacology},
  year={2008},
  volume={11 2},
  pages={207-16}
}
Chronic treatment of antipsychotic drugs can modulate gene expression in the brain, which may underscore their clinical efficacy. Aripiprazole is the first approved antipsychotic drug of the class of dopamine D2 receptor partial agonist, which has been shown to have similar efficacy and favourable side-effects profile compared to other antipsychotic drugs. This study aimed to identify differential gene expression induced by chronic treatment of aripiprazole. We used microarray-based gene… CONTINUE READING
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