Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations.

@article{Wolfson2000ChronicTO,
  title={Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations.},
  author={Marina Wolfson and Yuly Bersudsky and Evgeny Zinger and M E Simkin and Robert Haim Belmaker and Leif Hertz},
  journal={Brain research},
  year={2000},
  volume={855 1},
  pages={158-61}
}
Inositol uptake was measured at concentrations of 25, 40 and 50 microM in human astrocytoma cell cultures treated for 1-3 weeks with pharmacologically relevant concentrations of LiCl, valproic acid or carbamazepine as well as in control cultures that had not been treated with any drug. After at least 2 weeks of treatment, each of these 3 conventional anti… CONTINUE READING