Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

@article{Goldstein2012ChronicTE,
  title={Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.},
  author={Lee E. Goldstein and Andrew M. Fisher and Chad A. Tagge and Xiaolei Zhang and Libor Vel{\'i}{\vs}ek and John A P Sullivan and Chirag Upreti and Jonathan M. Kracht and Maria Ericsson and Mark W. Wojnarowicz and Cezar J. Goletiani and Giorgi M. Maglakelidze and N. F. Casey and Juliet A. Moncaster and Olga Minaeva and Robert D. Moir and Christopher J. Nowinski and Robert A. Stern and Robert C. Cantu and James Geiling and Jan Krzysztof Blusztajn and Benjamin L. Wolozin and Tsuneya Ikezu and Thor D. Stein and Andrew E. Budson and Neil W. Kowall and David A Chargin and Andre Sharon and Sudad Saman and Garth F. Hall and William C. Moss and Robin O. Cleveland and Rudolph E. Tanzi and Patric K. Stanton and Ann C. McKee},
  journal={Science translational medicine},
  year={2012},
  volume={4 157},
  pages={157le8; author reply 157lr5}
}
Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein-linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of… CONTINUE READING
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