Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma

@article{Baugh2012ChronicTE,
  title={Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma},
  author={Christine M Baugh and Julie M. Stamm and David O. Riley and Brandon E. Gavett and Martha Elizabeth Shenton and Alexander Peter Lin and Christopher J. Nowinski and Robert C. Cantu and Ann C. McKee and Robert A. Stern},
  journal={Brain Imaging and Behavior},
  year={2012},
  volume={6},
  pages={244-254}
}
Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease thought to be caused, at least in part, by repetitive brain trauma, including concussive and subconcussive injuries. It is thought to result in executive dysfunction, memory impairment, depression and suicidality, apathy, poor impulse control, and eventually dementia. Beyond repetitive brain trauma, the risk factors for CTE remain unknown. CTE is neuropathologically characterized by aggregation and accumulation of… 
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Potential neuroimaging modalities that may be capable of diagnosing CTE in vivo through the detection of tau and other known pathological features are discussed.
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Although CTE appears to be most prevalent among American football athletes, it is not restricted to this group of individuals and any individual who has been subjected to extensive brain injury throughout their life can develop CTE.
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