Chronic transplantation immunity in newts: temperature susceptibility of an effector phase in allo-skin graft rejection.

@article{Kinefuchi2011ChronicTI,
  title={Chronic transplantation immunity in newts: temperature susceptibility of an effector phase in allo-skin graft rejection.},
  author={Kenjiroh Kinefuchi and Yoshihiro Kushida and Masato Johnouchi and Yuiko Shimizu and Hikaru Ohneda and Masato Fujii and Masamichi Hosono},
  journal={Zoological science},
  year={2011},
  volume={28 7},
  pages={509-16}
}
Urodele amphibians are unique due to their greatly reduced immune responsiveness compared to bony fishes, which show acute immune responsiveness. In newts, the mean survival time of allogenic skin grafts in the transplantation immunity was 48.8 ± 8.3 days at 25°C, suggesting that it occurs in a chronic manner. The graft rejection process was categorized into three stages: a latent stage with frequent blood circulation, or the immune induction phase; a vascular stoppage stage with dominant… CONTINUE READING