Chronic toxicity of arsenic in goats: clinicobiochemical changes, pathomorphology and tissue residues.

@article{Sarkar2000ChronicTO,
  title={Chronic toxicity of arsenic in goats: clinicobiochemical changes, pathomorphology and tissue residues.},
  author={Sarkar and Bhowmik and Samanta and Biswas},
  journal={Small ruminant research : the journal of the International Goat Association},
  year={2000},
  volume={38 3},
  pages={229-235}
}
  • Sarkar, Bhowmik, +1 author Biswas
  • Published 2000 in
    Small ruminant research : the journal of the…
Chronic inorganic arsenic toxicity was induced in goats by oral administration of one-fifth of the acute lethal dose 50 (ALD(50)) of sodium arsenite (25mgkg(-1) body weight) packed in gelatin capsules and given daily for 12 weeks. Clinical signs of toxicity developed from 3 week post-exposure, consisting of gastrointestinal disturbances and renal insufficiency with 100% mortality in all animals. There were significant (p<0.01) decreases in total serum protein and the albumin: globulin ratio… CONTINUE READING