Chronic symptoms are common in patients with neuroborreliosis – a questionnaire follow‐up study

  title={Chronic symptoms are common in patients with neuroborreliosis – a questionnaire follow‐up study},
  author={Magnus Vrethem and Lisa Hellblom and M Widlund and M. Ahl and O. Danielsson and Jan Ernerudh and Pia Forsberg},
  journal={Acta Neurologica Scandinavica},
Vrethem M, Hellblom L, Widlund M, Ahl M, Danielsson O, Ernerudh J, Forsberg P. Chronic symptoms are common in patients with neuroborreliosis – a questionnaire follow‐up study. Acta Neurol Scand 2002: 106: 205–208. © Blackwell Munksgaard 2002. 

European neuroborreliosis: quality of life 30 months after treatment

Eikeland R, Mygland Å, Herlofson K, Ljøstad U. European neuroborreliosis: quality of life 30 months after treatment. 
Acta Neurol Scand: 2011: 124: 349–354. 
© 2011 John Wiley & Sons A/S.

Clinical manifestations and long‐term outcome of early Lyme neuroborreliosis according to the European Federation of Neurological Societies diagnostic criteria (definite versus possible) in central Europe. A retrospective cohort study

The characteristics and long‐term outcome of Lyme neuroborreliosis (LNB) according to diagnostic certainty (definite vs. possible) are incompletely understood.

Management of neuroborreliosis in European adult patients

The survey aims to survey present knowledge and controversies in European neuroborreliosis and to investigate the role of language and language-based learning in brain injury.

Remaining complaints 1 year after treatment for acute Lyme neuroborreliosis; frequency, pattern and risk factors

To chart remaining complaints 1’year after treatment for neuroborreliosis, and to identify risk factors for a non‐favorable outcome, is charted.

Neurologic manifestations of Lyme Borreliosis.

Neuroborreliosis--an epidemiological, clinical and healthcare cost study from an endemic area in the south-east of Sweden.

CSF analysis is necessary for the diagnosis of NB, because some patients develop antibodies in serum later than in CSF, and early diagnosis of borreliosis would result in reduced human suffering and in economic gain.

Prognose pädiatrischer Patienten nach Neuroborreliose

The prognosis of neuroborreliosis in childhood in central europe after early and adequate therapy to be very favorable.

EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis

Background:  Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb).

Risk factors for a non‐favorable outcome after treated European neuroborreliosis

To identify possible risk factors for reduced health‐related quality of life (HRQoL) and fatigue after treated Lyme neuroborreliosis (LNB), a large number of patients with known or suspected cases of Lyme disease were surveyed.

Relevance of immunological variables in neuroborreliosis and multiple sclerosis

The aims were to investigate the frequency of intrathecal synthesis of specific antibodies against measles, rubella and varicella zoster viruses as a diagnostic marker between multiple sclerosis and neuroborreliosis groups and to postulate the most typical cerebrospinal fluid variables profile of these entities.



Clinical and serologic follow-up in patients with neuroborreliosis

Although neurologic deficits decreased significantly, more than half of patients with clinical signs of neuroborreliosis had unspecific complaints resembling a chronic fatigue syndrome and showed persisting positive immunoglobulin M serum titers for Borrelia in the Western blot analysis.

Comments on the course and classification of Lyme borreliosis.

On the basis of answers by clinicians to a questionnaire concerning the classification and staging of Lyme borreliosis, the following classification is proposed: EARLY LYME BORRELIOSIS Localized

Clinical Manifestations and Diagnosis of Neuroborreliosis

Final evidence for the diagnosis is the demonstration of specific antibodies in serum and/or CSF, since these methods are complementary when trying to obtain a serological diagnosis of neuroborreliosis.

Variable CSF findings in early and late Lyme neuroborreliosis: A follow-up study in 47 patients

  • R. Kaiser
  • Medicine, Biology
    Journal of Neurology
  • 2004
Clinical recovery was usually accompanied by a considerable improvement of the blood-CSF barrier function and pleocytosis, and six months after antibiotic treatment, patients with ELN still revealed evidence of intrathecal synthesis of total IgM, whereas those with LLN did not.

Follow-up of patients treated with oral doxycycline for Lyme neuroborreliosis.

Oral doxycycline seems to be an effective, convenient and inexpensive alternative for the treatment of Lyme neuroborreliosis.

Neurological and psychological symptoms after the severe acute neuroborreliosis.

The results of this study suggest the existence of long-lasting consequences of acute neuroborreliosis, which can significantly influence the quality of life of patients.

Chronic forms of Borrelia burgdorferi infection of the nervous system

Three European patients had chronic active forms of Borrelia burgdorferi infection of the nervous system, with high titers of antibodies to this spirochete in serum and CSF, and responded to intravenous penicillin treatment.

The clinical and epidemiological profile of Lyme neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production.

It is concluded that neuroborreliosis is a common and characteristic neurological disorder and the diagnosis should be based on the demonstration of inflammatory CSF changes and B. burgdorferi specific intrathecal antibody production.

The Long-Term Clinical Outcomes of Lyme Disease: A Population-Based Retrospective Cohort Study

The prevalence of persistent symptoms in unselected patients with a history of Lyme disease was ascertained; their rheumatologic, neurologic, and health status outcomes were determined; and potential risk factors for these long-term sequelae were identified.

Practice parameters for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease)

The Quality Standards Subcommittee (QSS) of the American Academy of Neurology seeks to develop scientifically sound and clinically relevant practice parameters for neurologists to assist in clinical