Chronic sympathetic suppression in the treatment of chronic congestive heart failure.

@article{Manolis1998ChronicSS,
  title={Chronic sympathetic suppression in the treatment of chronic congestive heart failure.},
  author={Athanasios John Manolis and Christoforos Olympios and Maria D Sifaki and Nikos Smirnioudis and Stylianos M Handanis and S Argirakis and Christos Katsaros and Irene Gavras and Haralambos Gavras},
  journal={Clinical and experimental hypertension},
  year={1998},
  volume={20 7},
  pages={717-31}
}
Previous short-term studies demonstrated that treatment with clonidine produced significant hemodynamic improvement in patients with congestive heart failure (CHF). In this study we followed 12 CHF patients (10 M, 2 F age 63+/-11, 10 with ischemic cardiomyopathy and 2 with dilated cardiomyopathy) treated with 0.15 or 0.075 mg oral clonidine twice daily for 13+/-5 months (range 6-23). with functional evaluation at baseline, 6 weeks and 6 months. There was suppression of circulating… CONTINUE READING