Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS).

@article{Festa2000ChronicSI,
  title={Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS).},
  author={Andreas Festa and R. D'agostino and George Howard and Leena Mykk{\"a}nen and Russell P Tracy and Steven M. Haffner},
  journal={Circulation},
  year={2000},
  volume={102 1},
  pages={
          42-7
        }
}
BACKGROUND Inflammation has been suggested as a risk factor for the development of atherosclerosis. Recently, some components of the insulin resistance syndrome (IRS) have been related to inflammatory markers. We hypothesized that insulin insensitivity, as directly measured, may be associated with inflammation in nondiabetic subjects. METHODS AND RESULTS We studied the relation of C-reactive protein (CRP), fibrinogen, and white cell count to components of IRS in the nondiabetic population of… CONTINUE READING

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