Chronic stress enhances the corticosterone response and neurotoxicity to +3,4-methylenedioxymethamphetamine (MDMA): the role of ambient temperature.

@article{Johnson2010ChronicSE,
  title={Chronic stress enhances the corticosterone response and neurotoxicity to +3,4-methylenedioxymethamphetamine (MDMA): the role of ambient temperature.},
  author={Bethann N. Johnson and Bryan K. Yamamoto},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2010},
  volume={335 1},
  pages={180-9}
}
Stress facilitates drug abuse by humans. In rodents, stress enhances the neurochemical, neuroendocrine, and behavioral responses to psychostimulants. Although chronic unpredictable stress (CUS) enhances the acute hyperthermic and long-term monoamine-depleting effects of the psychostimulant +3,4-methylenedioxymethamphetamine (MDMA), the roles of hyperthermia and corticosterone (CORT) in mediating the stress-induced enhancement of MDMA-induced serotonin (5-HT) and dopamine (DA) depletions are… CONTINUE READING
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Chronic unpredictable stress regulates hypothalamic 5 HT 2 A receptor transcription and function and potentiates methamphetamine increases in hyperthermia and corticosterone

  • J Raudensky, BK Yamamoto
  • Abstr Soc Neurosci
  • 2008
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