Chronic stress alters dendritic morphology in rat medial prefrontal cortex.

@article{Cook2004ChronicSA,
  title={Chronic stress alters dendritic morphology in rat medial prefrontal cortex.},
  author={S. C. Cook and Cara L Wellman},
  journal={Journal of neurobiology},
  year={2004},
  volume={60 2},
  pages={
          236-48
        }
}
Chronic stress produces deficits in cognition accompanied by alterations in neural chemistry and morphology. Medial prefrontal cortex is a target for glucocorticoids involved in the stress response. We have previously demonstrated that 3 weeks of daily corticosterone injections result in dendritic reorganization in pyramidal neurons in layer II-III of medial prefrontal cortex. To determine if similar morphological changes occur in response to chronic stress, we assessed the effects of daily… CONTINUE READING
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