156 Citations
Biofilm presence in humans with chronic suppurative otitis media
- MedicineOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- 2009
Biofilms in Chronic Rhinosinusitis with Nasal Polyps
- MedicineOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- 2011
Biofilms were present in patients undergoing functional endoscopic sinus surgery for CRSwNP and also in controls without chronic sinusitis, suggesting that biofilms may not be sufficient to cause chronic Sinusitis without other cofactors.
Correlation of Bacterial Biofilm Grade with Clinical Features in Chronic Rhinosinusitis
- Medicine
- 2013
A grading system for biofilms is essential and it should be established in order to perceive CRS pathophysiology and find new treatment targets.
The pathophysiological role of bacterial biofilms in chronic sinusitis
- Medicine, BiologyEuropean Archives of Oto-Rhino-Laryngology
- 2015
Assessment of the sinuses’ microflora and biofilm formation on the sino-nasal mucosa in patients with CRS suggests that this convoluted three-dimensional structures might play a significant role in either the pathogenesis or persistence of chronic rhinosinusitis.
The Effect of Spray Cryotherapy on Microbial Biofilms in Chronic Rhinosinusitis
- Medicine, BiologyCurrent Infectious Disease Reports
- 2018
Cryotherapy has proven to be a reliable method for the disruption of microbial biofilms in CRS with nasal polyps, in vitro conditions and could be a considerable benefit in the management of recalcitrant CRS.
Damage to Ciliated Epithelium in Chronic Rhinosinusitis: What is the Role of Bacterial Biofilms?
- MedicineThe Annals of otology, rhinology, and laryngology
- 2008
The data support the hypothesis that biofilm formation represents the latter phase of an inflammatory process that leads to complete epithelial destruction in patients with chronic rhinosinusitis.
Bacterial biofilms in chronic rhinosinusitis and their relationship with inflammation severity.
- MedicineAuris, nasus, larynx
- 2012
Clinical Factors Associated with Bacterial Biofilm Formation in Chronic Rhinosinusitis
- MedicineOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- 2011
The results of this study suggest that the probability of bacterial biofilm formation is independent of many clinical factors considered to be risk factors for chronic rhinosinusitis.
Clinical Characteristics of Biofilms in Patients with Chronic Rhinosinusitis: A Prospective Case–Control Study
- MedicineIndian Journal of Otolaryngology and Head & Neck Surgery
- 2014
The presence of bacterial biofilms may contribute to the pathogenesis of chronic rhinosinusitis and the clinical characteristics of CRS patients after endoscopic sinus surgery is suggested.
Bacterial Biofilms in Chronic Rhinosinusitis
- Medicine, BiologyThe Annals of otology, rhinology & laryngology. Supplement
- 2006
The laboratory has identified the presence of biofilms in sinonasal mucosa isolated from human patients and on stents removed after frontal sinus surgery, andBiofilms have been found on the sinus epithelium of rabbitsinfected with Pseudomonas aeruginosa, but not in rabbits infected with non-biofilm-forming P aerug inosa mutants.
References
SHOWING 1-10 OF 17 REFERENCES
Adult Chronic Rhinosinusitis: Definitions, Diagnosis, Epidemiology, and Pathophysiology
- MedicineOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- 2003
Is otitis media with effusion a biofilm infection?
- MedicineClinical otolaryngology and allied sciences
- 2004
Evidence that otitis media with effusion may represent a chronic infective state such as those evidenced in conditions secondary to biofilms or small colony variants is discussed and why this may be important in the future management of this condition is explained.
Forging a Link Between Biofilms and Disease
- MedicineScience
- 1999
The sticky conglomerations of bacteria known as biofilms are being linked to common human diseases ranging from tooth decay to prostatitis and kidney infections, and a new program at the National Institutes of Health is working to understand how and why they form.
Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
- BiologyNature
- 2000
The hypothesis that P. aeruginosa might exist as biofilms—structured communities of bacteria encased in a self-produced polymeric matrix—in the cystic fibrosis lung is supported by microscopy of cystic Fibrosis sputum, which shows that the bacterium are in biofilm-like structures.
Biofilms: Microbial Life on Surfaces
- BiologyEmerging infectious diseases
- 2002
A greater understanding of biofilm processes should lead to novel, effective control strategies for biofilm control and a resulting improvement in patient management.
Bacterial biofilms: a common cause of persistent infections.
- Medicine, BiologyScience
- 1999
Improvements in understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.
Detection of Differential Gene Expression in Biofilm-Forming versus Planktonic Populations of Staphylococcus aureus Using Micro-Representational-Difference Analysis
- BiologyApplied and Environmental Microbiology
- 2001
To identify genes which are typically expressed in biofilms, a micro-representational-difference analysis (micro-RDA) was adapted for gram-positive bacteria and used with cDNA derived from populations of S. aureus growing in a biofilm or plankonically.
Bacterial resistance to antibiotics: the role of biofilms.
- Medicine, BiologyProgress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
- 1991
Bacteria adhere to natural and synthetic, medically important surfaces within an extracellular polymer generically termed the glycocalyx. This quasi-structure is a biofilm. The enhanced antibiotic…
Bacterial resistance to antibiotics: the role of biofilms.
- Medicine, Biology
- 1991
Bacteria adhere to natural and synthetic, medically important surfaces within an extracellular polymer generically termed the glycocalyx. This quasi-structure is a biofilm. The enhanced antibiotic…
The involvement of cell-to-cell signals in the development of a bacterial biofilm.
- Biology, MedicineScience
- 1998
The involvement of an intercellular signal molecule in the development of Pseudomonas aeruginosa biofilms suggests possible targets to control biofilm growth on catheters, in cystic fibrosis, and in other environments where P. aerug inosaBiofilms are a persistent problem.