Chronic relapsing (dysimmune) polyneuropathy: pathogenesis and treatment.

  title={Chronic relapsing (dysimmune) polyneuropathy: pathogenesis and treatment.},
  author={Marinos C. Dalakas and W. King Engel},
  journal={Annals of neurology},
  volume={9 Suppl},
Chronic relapsing polyneuropathy is a distinct dysschwannian/demyelinating polyneuropathy characterized by usually slow onset, progressive or relapsing-remitting course, elevated cerebrospinal fluid (CSF) protein, marked slowing of nerve conduction velocity, segmental demyelination demonstrable in sural nerve biopsies, and absence of systemic illness or abnormal serum immunoglobulins. The cause of the disorder and the mechanisms underlying its chronicity and relapsing-remitting course are not… CONTINUE READING


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