Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.

@article{Peters2012ChronicPS,
  title={Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.},
  author={Sebastian Thomas Peters and Nicole Grunwald and Petra R{\"u}mmele and Esther Endlicher and Anja Lechner and Inga D. Neumann and Florian Obermeier and Stefan O Reber},
  journal={Stress},
  year={2012},
  volume={15 4},
  pages={
          403-15
        }
}
Patients with inflammatory bowel diseases (IBDs) have a higher risk of developing colorectal cancer (CRC) than the general population. Furthermore, chronic psychosocial stress increases the likelihood of developing IBD and multiple types of malignant neoplasms, including CRC. Here, for the first time, we investigate the effects of chronic psychosocial stress in male mice on an artificially induced CRC, by employing the chronic subordinate colony (CSC) housing paradigm in combination with the… CONTINUE READING
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