Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig.

@article{Iqbal2005ChronicPE,
  title={Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig.},
  author={Umar Iqbal and James F. Brien and Sonja Banjanin and Marcus H. Andrews and Stephen G. Matthews and James N. Reynolds},
  journal={Journal of neuroendocrinology},
  year={2005},
  volume={17 9},
  pages={600-8}
}
The present study tested the hypothesis that chronic prenatal ethanol exposure causes long-lasting changes in glucocorticoid signalling in postnatal offspring. Pregnant guinea pigs were treated with ethanol (4 g/kg maternal body weight/day), isocaloric-sucrose/pair-feeding or water throughout gestation, and maternal saliva cortisol concentration was determined 2 h after treatment at different stages of gestation. Electrically-stimulated release of glutamate and GABA, in the presence or absence… CONTINUE READING
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