Chronic pain therapy and hypothalamic-pituitary-adrenal axis impairment

@article{Aloisi2011ChronicPT,
  title={Chronic pain therapy and hypothalamic-pituitary-adrenal axis impairment},
  author={Anna Maria Aloisi and Michelangelo Buonocore and Laura Merlo and Caterina Galandra and Cesare Bonezzi},
  journal={Psychoneuroendocrinology},
  year={2011},
  volume={36},
  pages={1032-1039}
}
Opiates and/or nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most effective therapies for chronic pain, but their prolonged time of use can affect health conditions through physical and psychological side effects. They include the very common gastrointestinal effects and changes that can induce osteoporosis, depression, impaired cognition and a generally poor quality of life, which per se can induce and maintain a chronic painful condition. For this reason it is becoming… CONTINUE READING
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