Chronic oral administration of arginine induces GH gene expression and insulin resistance.

@article{Barbosa2006ChronicOA,
  title={Chronic oral administration of arginine induces GH gene expression and insulin resistance.},
  author={Tha{\'i}s de Castro Barbosa and Leonice Lourenço Poyares and Ubiratan Fabres Machado and Maria Tereza Nunes},
  journal={Life sciences},
  year={2006},
  volume={79 15},
  pages={1444-9}
}
Arginine (Arg) presents a potent growth hormone (GH) releasing activity. In vivo and in vitro studies carried out in our laboratory have demonstrated that acute treatment with Arg also increases GH gene expression. Taking into account the recognizable diabetogenic role of GH and that Arg increases insulin release, this study aimed at evaluating the effects of oral chronic administration of Arg on GH gene expression, by Northern blotting analysis, and on the insulin sensitivity, by means of the… CONTINUE READING

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