Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study.

@article{Andersen2011ChronicOP,
  title={Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study.},
  author={Zorana Jovanovic Andersen and Martin Hvidberg and Steen Solvang Jensen and Matthias Ketzel and Steffen Loft and Mette S{\o}rensen and Anne Tj{\o}nneland and Kim Overvad and Ole Raaschou-Nielsen},
  journal={American journal of respiratory and critical care medicine},
  year={2011},
  volume={183 4},
  pages={
          455-61
        }
}
RATIONALE Short-term exposure to air pollution has been associated with exacerbation of chronic obstructive pulmonary disease (COPD), whereas the role of long-term exposures on the development of COPD is not yet fully understood. OBJECTIVES We assessed the effect of exposure to traffic-related air pollution over 35 years on the incidence of COPD in a prospective cohort study. METHODS We followed 57,053 participants in the Danish Diet, Cancer, and Health cohort in the Hospital Discharge… 
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TLDR
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Long-term exposure to traffic-related air pollution increases the risk for asthma hospitalisation in older people, and people with previous asthma or COPD hospitalisations are most susceptible.
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TLDR
Higher levels of ambient air pollution were significantly associated with more symptoms and an increased risk of experiencing an exacerbation, suggesting that measurement of indoor levels of pollutants in persons who spend considerable time indoors (such as those with significant COPD) may be a more relevant measure of exposure than outdoor levels more commonly assessed.
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TLDR
Older age, male sex, preexisting heart conduction disorders, and cerebrovascular diseases were associated with stronger effects in COPD subjects, suggesting a need for more protective air pollution standards for susceptible groups.
Impact of Long-term Exposure to Ambient Air Pollution on the Incidence of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.
TLDR
A systematic review and meta-analysis showed that long-term exposure to PM2.5 and NO2 can be associated with increased incidence of COPD.
Association of ambient air pollution with the prevalence and incidence of COPD
TLDR
None of the principal results were statistically significant, the weak positive associations of exposure with COPD and the significant subgroup findings need to be evaluated in further well standardised cohorts followed up for longer time, and with time-matched exposure assignments.
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TLDR
Evidence of chronic effects of air pollution on the prevalence and incidence of COPD among adults was suggestive but not conclusive, despite plausible biological mechanisms and good evidence that air pollution affects lung development in childhood and triggers exacerbations in COPD patients.
Long-term exposure to low concentrations of air pollutants and hospitalisation for respiratory diseases: A prospective cohort study in Australia.
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Weak positive associations of exposure to air pollution with hospitalisation for asthma while there was no evidence of an association for all respiratory diseases are found.
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