Chronic nicotinic stimulation and blockade effects on working memory.

  title={Chronic nicotinic stimulation and blockade effects on working memory.},
  author={E D Levin and S R Briggs and N. C. Christopher and J Rose},
  journal={Behavioural pharmacology},
  volume={4 2},
Acute and chronic nicotine treatment has been found to improve learning and memory function in a variety of tasks. In several studies we have found that chronic nicotine infusion improves working memory performance. Replicating these results, the current study showed that chronic nicotine treatment (12mg/kg/day) significantly improved working memory performance in the radial-arm maze. The nicotine effect did not diminish during the 2 weeks following withdrawal. The nicotine-induced improvement… CONTINUE READING

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