Chronic nicotine pretreatment is sufficient to upregulate a4* nicotinic receptors and increase oral nicotine self-administration in mice

Abstract

Background: Understanding the underlying causes of nicotine addiction will require a multidisciplinary approach examining the key molecular, cellular and neuronal circuit functional changes that drive escalating levels of nicotine self-administration. In this study, we examined whether mice pretreated with chronic nicotine, at a dosing regimen that results… (More)

Topics

9 Figures and Tables

Cite this paper

@inproceedings{Renda2014ChronicNP, title={Chronic nicotine pretreatment is sufficient to upregulate a4* nicotinic receptors and increase oral nicotine self-administration in mice}, author={Anthony Renda and Raad Nashmi}, year={2014} }