Chronic myelogenous leukaemia ( CML )

Evidence exists for the involvement of the most primitive and quiescent hematopoietic stem cell compartiment (CD34+/CD38-, Thy1+): t(9;22) is found in myeloid progenitor and in B-lymphocytes progenitors, but, involvement of the T-cell lineag is extremely rare. The existence of a highly quiescent stem cell population has been demonstrated in patie nts with… CONTINUE READING