Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of diagnostic utility.

Abstract

Chronic mucocutaneous candidiasis (CMC) is characterized by recurrent and persistent superficial infections, with Candida albicans affecting the mucous membranes, skin and nails. It can be acquired or caused by primary immune deficiencies, particularly those that impair interleukin (IL)-17 and IL-22 immunity. We describe a single kindred with CMC and the… (More)
DOI: 10.1111/cei.12746

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@article{Dhalla2016ChronicMC, title={Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of diagnostic utility.}, author={Fatima Dhalla and H. Fox and Ellen Davenport and Ross S Sadler and Consuelo Anzilotti and Pauline A van Schouwenburg and B Ferry and Helen M. Chapel and J. C. Knight and S Y Patel}, journal={Clinical and experimental immunology}, year={2016}, volume={184 2}, pages={216-27} }