Chronic motor neuropathies: diagnosis, therapy, and pathogenesis.

  title={Chronic motor neuropathies: diagnosis, therapy, and pathogenesis.},
  author={Andrew J. Kornberg and Alan Pestronk},
  journal={Annals of neurology},
  volume={37 Suppl 1},
Pure motor neuropathy syndromes resemble amyotrophic lateral sclerosis variants with no upper motor neuron signs. Their identification is important, as, in contrast to amyotrophic lateral sclerosis, they are often immune mediated and treatable. Typically the immune-mediated motor neuropathy syndromes are distal and asymmetrical and progress slowly. The clinical features may help alert the clinician to the diagnosis, but other ancillary evidence such as abnormalities on electrophysiological… CONTINUE READING