Chronic morphine alters calbindin D-28k immunostaining patterns in mouse forebrain.

@article{Maharajan1998ChronicMA,
  title={Chronic morphine alters calbindin D-28k immunostaining patterns in mouse forebrain.},
  author={P A Maharajan and R Prencipe and Roberto Falchetti and Paolo di Francesco and Giuseppe Paino and Veeramani Maharajan},
  journal={Neuroscience letters},
  year={1998},
  volume={243 1-3},
  pages={65-8}
}
The influence of chronic morphine treatment on the brain of adult mouse has been studied. Female Swiss mice were daily administered saline or morphine (30 or 60 mg/kg body weight) for a period comprising 7 days before mating, during gestation and until 21 days post-partum. Their brains were then perfusion-fixed and examined for histology and calbindin D-28k protein-immunoreactivity. Histological observations revealed no significant changes in the various brain regions; whereas a reduced number… CONTINUE READING

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