Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats.

@article{Kompagne2008ChronicMS,
  title={Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats.},
  author={Hajnalka Kompagne and Gy{\"o}rgy B{\'a}rdos and G{\'a}bor Sz{\'e}n{\'a}si and Istv{\'a}n Gacs{\'a}lyi and L{\'a}szl{\'o} G{\'a}bor H{\'a}rsing and Gy{\"o}rgy L{\'e}vay},
  journal={Behavioural brain research},
  year={2008},
  volume={193 2},
  pages={311-4}
}
A 3-week chronic mild stress (CMS) protocol decreased sucrose preference of rats and increased immobility in the forced swim test. It also induced social avoidance and increased grooming, but acted as if reducing anxiety in the plus-maze. Sucrose preference and social avoidance, but not other measures of the behaviour, showed significant correlation. We conclude that CMS-induced depression-like behaviour is associated with social avoidance, a seemingly anxiety-related measure, but not with… CONTINUE READING

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