Chronic mild stress facilitates melanoma tumor growth in mouse lines selected for high and low stress-induced analgesia.

@article{Ragan2013ChronicMS,
  title={Chronic mild stress facilitates melanoma tumor growth in mouse lines selected for high and low stress-induced analgesia.},
  author={Agnieszka R. Ragan and Anna Lesniak and Marta Bochyńska-Czyż and Anna Kosson and Hanna Szymanska and Kazimiera Pyśniak and Marta Gajewska and Andrzej Wojciech Lipkowski and Mariusz Sacharczuk},
  journal={Stress},
  year={2013},
  volume={16 5},
  pages={
          571-80
        }
}
Both chronic stress conditions and hyperergic reaction to environmental stress are known to enhance cancer susceptibility. We described two mouse lines that displayed high (HA) and low (LA) swim stress-induced analgesia (SSIA) to investigate the relationship between inherited differences in sensitivity to stress and proneness to an increased growth rate of subcutaneously inoculated melanoma. These lines display several genetic and physiological differences, among which distinct sensitivity to… CONTINUE READING

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