Chronic lymphocytic leukemia B cells inhibit spontaneous Ig production by autologous bone marrow cells: role of CD95-CD95L interaction.

Abstract

A variable degree of humoral immunodeficiency is a common feature in patients with B-cell chronic lymphocytic leukemia (B-CLL). The aim of this study was to explore the possibility that B-CLL cells play a direct role in this phenomenon. To this end, patients' bone marrow (BM) immunoglobulin (Ig)-secreting cells were cocultured with autologous purified B-CLL… (More)

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@article{Sampalo2000ChronicLL, title={Chronic lymphocytic leukemia B cells inhibit spontaneous Ig production by autologous bone marrow cells: role of CD95-CD95L interaction.}, author={Almudena Sampalo and Gwyneth Navas and Francisco Medina and Carmen Segundo and Carlos Augusto Canteras Raposo Camara and J. Brieva}, journal={Blood}, year={2000}, volume={96 9}, pages={3168-74} }