Chronic low-level arsenic exposure causes gender-specific alterations in locomotor activity, dopaminergic systems, and thioredoxin expression in mice.

@article{Bardullas2009ChronicLA,
  title={Chronic low-level arsenic exposure causes gender-specific alterations in locomotor activity, dopaminergic systems, and thioredoxin expression in mice.},
  author={Ulises Bardullas and Jorge H Lim{\'o}n-Pacheco and Magda Giordano and Leticia Carrizales and Mar{\'i}a Soledad Mendoza-Trejo and Ver{\'o}nica M Rodr{\'i}guez},
  journal={Toxicology and applied pharmacology},
  year={2009},
  volume={239 2},
  pages={169-77}
}
Arsenic (As) is a toxic metalloid widely present in the environment. Human exposure to As has been associated with the development of skin and internal organ cancers and cardiovascular disorders, among other diseases. A few studies report decreases in intelligence quotient (IQ), and sensory and motor alterations after chronic As exposure in humans. On the other hand, studies of rodents exposed to high doses of As have found alterations in locomotor activity, brain neurochemistry, behavioral… CONTINUE READING