Chronic ketamine exposure induces permanent impairment of brain functions in adolescent cynomolgus monkeys

@article{Sun2014ChronicKE,
  title={Chronic ketamine exposure induces permanent impairment of brain functions in adolescent cynomolgus monkeys},
  author={Lin Sun and Qi Li and Qing Li and Yuzhe Zhang and De-xiang Liu and H. Jiang and F. Pan and D. Yew},
  journal={Addiction Biology},
  year={2014},
  volume={19}
}
Ketamine, a non‐competitive N‐methyl‐D‐aspartic acid receptor antagonist, has emerged as an increasingly popular drug among young drug abusers worldwide. Available evidence suggests that ketamine produces acute impairments of working, episodic and semantic memory along with psychotogenic and dissociative effects when a single dose is given to healthy volunteers. However, understanding of the possible chronic effects of ketamine on behavior, cognitive anomalies and neurochemical homeostasis is… Expand
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