Chronic intrahepatic cholestasis in sickle cell disease requiring exchange transfusion.

@article{OCallaghan1995ChronicIC,
  title={Chronic intrahepatic cholestasis in sickle cell disease requiring exchange transfusion.},
  author={Alan O'Callaghan and Stephen G. O'Brien and Marina Ninkovi{\'c} and George Butcher and ChristopherS. Foster and Julian R. F. Walters and IreneA. G. Roberts},
  journal={Gut},
  year={1995},
  volume={37 1},
  pages={
          144-7
        }
}
A 15 year old boy with sickle cell disease developed intrahepatic cholestasis. A course of exchange transfusion successfully corrected the extreme hyperbilirubinaemia over one year. Upon stopping the exchange transfusion programme the hyperbilirubinaemia relapsed but transfusion was effective when reinstituted. 
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